Benefits the objectives of the hhs final rule are to create a means of ensuring enhanced oversight in the transfer storage and use of select agents and toxins clarify that an entity must use a validated method to render a select agent non viable or a regulated infectious nucleic acid sample non infectious for future use and require that . Subtitle a of title ii of the public health security and bioterrorism preparedness and response act of 2002 42 usc 262a requires hhs to regulate the possession use and transfer of biological agents or toxins that the hhs secretary determines have the potential to pose a severe threat to public health and safety select agents and toxins. We proposed to add a requirement that the responsible officials regular place of employment or principal duty station must be located in close proximity to the physical location of the registered entity entered in section 1a of aphis cdc form 1 application for registration for possession use and transfer of select agents and toxins. The federal select agent program oversees the possession use and transfer of biological select agents and toxins which have the potential to pose a severe threat to public animal or plant health or to animal or plant products the program greatly enhances the nations oversight of the safety and security of select agents by. Download citation on researchgate possession use and transfer of select agents and toxins biennial review final rule in accordance with the public health security and bioterrorism
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